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1
Nutrition Talk / Cervical Polyp
« Last post by jillirish on Today at 06:23:21 AM »
I am looking for some information on cervical polyps and the best way to address holistically.  There was a form post made back in 2012 on uterine polyps and I am wondering if the advice is the same for cervical polyps. 

For estrogen dominance take Amino D-Tox and Esto-DIM and eat lots of cruciferous veggies, eggs and clean proteins?

Thanks!

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Nutrition Talk / Re: Oral Health
« Last post by jillirish on Today at 06:00:42 AM »
Thanks so much for the reply.  This information has been very helpful!
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Nutrition Talk / Re: Cleanse/fasting
« Last post by mattoconnor on September 12, 2018, 08:03:41 PM »
Britney,

That is great you are considering a cleanse.  It’s one of the best things you can do for yourself. Despite you wanting to do a short 5 day regiment, the cleanse I have in mind is a bit  longer-- 14 days.  However, that does not mean you can’t tinker with the cleanse to suit your lifestyle needs.  The one I highly recommend is the EJUVA herbal intestinal cleanse....www.ejuva.com.  It’s a cleanse that gained a great amount of notoriety among the raw food movement in the early 2000s.  Ejuva consists of Chinese, Ayurvedic, and Western herbs and is the only cleansing program in the world that approaches physiological elimination and cleansing from a balanced Western, Ayurvedic, and Chinese medicine point of view.  In completing the cleanse several months ago, my weight diminished to the 140-150lb. range and energy levels were very close to optimal.     A close friend recommended the cleanse because of its “gentleness” and his ability to maintain a structured work schedule.  The Ejuva program is a 4 phase cleanse that can be done in 12 days( 3days per phase) or up to 30 days to loosen and eliminate toxic material gradually and lessen its negative impact on the body.  The foods that are recommended to eat that do not interfere with the body’s ability to eliminate toxins and waste products are raw, fresh, organic fruits and vegetables.  As you move through each phase you are eating 1 less meal.   Also, you are taking herbals supplements throughout each phase. You also incorporate juicing into the later phases. I personally juiced with Granny Smith apples since they have the lowest glycemic index in the apple family.  Britney, if I can be of any help please let me know.  I am a new student with a nursing background.  best of luck,  Matt
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Nutrition Talk / Re: Lectins and thyroid
« Last post by James on September 11, 2018, 05:44:07 PM »
This came up in an email a friend sent to me because she was reading some stuff on the supposed toxicity of lectins by this guy Grundy. This was my response:

"One of the big things about diet is there is so much speculation. For instance with Grundy his basis is the toxicity of the lectins. But if someone else comes along they can point out the toxicity of many of the foods he claims are alright to eat such as the strong goitrogenic effect of the flax seeds he says are OK or the high oxalic acid content of the purslane he claims is fine to eat."

Of course Gundry sells a lectin blocker so he has a financial incentive to hype of the dangers of lectins.

We also have top keep in mind that there are various types of lectins and to to imply that all are dangerous is ridiculous. That like saying because one plant fruit is poisonous this means all plant fruits are poisonous.

Also I looked in to some of the research instead of what is simply being repeated on the internet without fact checking. I can find very little backing Gundry's claims and what I could find was discussing cell cultures.  What happens in a Petri dish is not always the same as what happens in the body since in the body there are factors that can change the results such as metabolism, lack of absorption, digestion, etc.  Another factor is binding, which could be the case with lectins. Lectins can bind with carbohydrates, which are part of diet, but not part of the Petri dish culture studies I have seen. So this brings up the question does the carbohydrate binding of the lectins in diet block or reduce lectin absorption. Just like how dietary oxalate levels have very little to do with blood oxalate levels since dietary oxalates bind with minerals such as calcium in the diet preventing their absorption.  So we cannot rely on and apply Petri dish studies to how things work in the body yet that is what a lot of people seem to be trying to do.

Gundry even goes as far as claiming the lectins induce autoimmune hypothyroidism yet this study states one of the roles of lectins is to prevent autoimmune reactions:

https://www.ncbi.nlm.nih.gov/pubmed/12223269

"Biochim Biophys Acta. 2002 Sep 19;1572(2-3):187-97.

Animal lectins: a historical introduction and overview.

Kilpatrick DC1.

Author information

Abstract

Some proteins we now regard as animal lectins were discovered before plant lectins, though many were not recognised as carbohydrate-binding proteins for many years after first being reported. As recently as 1988, most animal lectins were thought to belong to one of two primary structural families, the C-type and S-type (presently known as galectins) lectins. However, it is now clear that animal lectin activity is found in association with an astonishing diversity of primary structures. At least 12 structural families are known to exist, while many other lectins have structures apparently unique amongst carbohydrate-binding proteins, although some of those "orphans" belong to recognised protein families that are otherwise not associated with sugar recognition. Furthermore, many animal lectins also bind structures other than carbohydrates via protein-protein, protein-lipid or protein-nucleic acid interactions. While animal lectins undoubtedly fulfil a variety of functions, many could be considered in general terms to be recognition molecules within the immune system. More specifically, lectins have been implicated in direct first-line defence against pathogens, cell trafficking, immune regulation and prevention of autoimmunity."
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Nutrition Talk / Re: probiotic supplement recommendations
« Last post by James on September 09, 2018, 11:01:42 PM »
I prefer cultured foods, such as milk kefir for several reasons.

First reason is that most probiotics are very limited in the number of strains there are. Even though we cannot provide additional levels of all of the thousands of beneficial strains found in our body it helps to provide as many strains as possible. Most probiotic supplements contain one to about 18 strains of beneficial bacteria. Milk kefir has around 22 beneficial strains of bacteria and yeast.

Secondly a lot of probiotic supplements are of questionable activity since there is no way to tell how long they sat around as raw material, how long as a finished product, of they were shipped by UPS or the Post Office in their non-air-conditioned trucks in the heat of summer, etc. Kefir is freshly made and is kept refrigerated even during shipping.  If you let it sit for a few weeks capped you will notice the container starting to expand. This does not mean it is going bad, it shows the cultures are live and active. The bacteria are fermenting the sugars in the kefir, which produces carbon dioxide gas that expands the container. This decreases the sugar content and increases the levels of beneficial acids in the product making it more sour. The fermentation continues until all the fermentable sugar is used up.

More important than probiotics are prebiotics. Probiotics are great for cases of food poisoning or a jump start after antibiotic use. But again no probiotic source will replace all the thousands of beneficial strains of flora. The good news is that antibiotics don't kill all your flora. There will always be some survivors and those need to be fed to rebuild their numbers. This is where prebiotics really come in to play.

As for Candida the biggest mistake people make is they try to kill the Candida, which simply does not work. Keep in mind that Candida is a normal part of our flora in its benign yeast form.  It is only pathogenic in its fungal form and the form is determined by pH. In a normal acidic environment the Candida growth gene turns off and the Candida remains in its benign yeast form. In an alkaline pH, such as when the beneficial acid producing flora are reduced by antibiotic use the Candida growth gene is turned on and the Candida morphs in to its pathogenic fungal form. In its fungal form the Candida forms finger-like projections called hyphae that allow the Candida to dig in to tissues leading to damage and inflammation.

Because Candida is a normal part of the flora trying to kill it does not really work since as with the bacteria you are never going to kill them all off. And if the pH of the terrain is not restored to the proper acidic pH the Candida growth gene remains on and the Candida remains in its pathogenic fungal form.

There are herbs such as lapacho (ipe roxi, pau d' arco,. taheebo, etc.) that are effective in knocking back the Candida temporarily but again they do not change the pH of the terrain to stop the Candida growth nor to keep it in its benign yeast form. Therefore I do not recommend this as a long term solution but rather a temporary symptom reliever until the flora can be restored.

Another tactic some people try are the enzymes cellulase and hemicellulase to attack the Candida. In my opinion this is the worst idea ever and I did a video on this exact topic years ago.  Our flora do produce tiny amounts of cellulase and hemicellulase allowing them to break down the cellulose and hemicellulose in the fibers we ingest. These enzymes will break these fibers down in to their individual glucose units that they can then use as a food source for the fermentation.

The enzymes are believed to digest the cellulose and hemicellulose in the Candida cell walls. Although there is the question if the enzymes actually reach the Candida to begin with since enzymes can be digested by our digestive system just like other proteins. And even if the enzymes manage to somehow avoid digestion the next question is will they work in the pH of the terrain? Some enzymes function in an acidic environment and others in an alkaline environment.

Another big problem with these enzyme products is that the enzymes will pre-digest the probiotic fibers. This not only starves the flora of its food source but also increases blood sugar levels due to the increased glucose formation. Therefore these enzymes starve the flora reducing the necessary acid formation to control the Candida all while increasing glucose levels to feed the Candida.
6
Nutrition Talk / Re: Women's Health/Osteoporosis/Hormone Replacement
« Last post by James on September 09, 2018, 02:37:19 AM »
Hi Jennifer,

For now it is helpful to support bones and hormone balance with a whole foods diet, avoiding acid forming foods like soda, sugar, caffeine, alcohol, refined white flour and excess animal food consumption. 

Sorry but I just have to say something here because this is a major pet peeve of mine when people claim "acid forming foods"..  ALL FOODS metabolize in to acids, this is basic human physiology. And ironically plants metabolize in to more acids than meats.

Some foods can contribute to bone loss such as colas, but not all sodas, and caffeine. This has absolutely nothing to do with pH though as foods do not alter our pH to begin with. The body has multiple redundant systems to maintain our pH, and diet is not one of them.  All foods are made acidic or more acidic in the stomach. Any acids in the chyme as it leaves the stomach is then neutralized as the chyme leaves the stomach through the release of pancreatic bicarbonate. So dietary acids do not even survive to alter our pH. In the long run the metabolism of the sugars, fatty acids and some amino acids by the cells leads to the production of acidic protons that are utilized by the body, neutralized or eliminated to maintain things like our pH, tissue oxygenation and circulation.

Colas can lead to bone loss due to their high phosphorus content. Same thing with red meats. When there is an excess of phosphate absorption an imbalance between the phosphate and serum calcium levels. This is perceived by the body as low serum calcium and the parathyroid glands respond by releasing  parathyroid hormone (PTH), which in turn releases calcium from the  bones to raise serum calcium to balance it out with the increased phosphorus. This is pseudohyperparathyroidism, which differs from hyperparathyroidism that is most often due to benign parathyroid tumors.

Caffeine increases the release of cortisol, which in excess also breaks bone down by decreasing calcium absorption and by inhibiting osteoblasts.

I know some people are going to be upset with me for saying this but I have been in medicine for nearly 40 years with nearly 30 of that working in an teaching holistic medicine. And I have worked extremely hard writing on the topic and presenting evidence from the medical journals and doing videos to support holistic medicine to help get it legitimized. When incorrect information is promoted this discredits, not promotes, holistic medicine..
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Nutrition Talk / Re: Women's Health/Osteoporosis/Hormone Replacement
« Last post by James on September 09, 2018, 02:07:10 AM »
A major reason for there being so many opinions on osteoporosis is due to most people, including doctors, do not really understand what osteoporosis is. May sound odd but it is true. Look at what most people including doctors recommend for osteoporosis. Mainly calcium and bisphosphonate drugs, neither of which correct osteoporosis. Why? Because if they look in to it they will find that osteoporosis IS NOT a loss of bone minerals. Those conditions are known as osteopenia and osteomalacia. Osteoporosis is a loss of bone collagen matrix reducing mineral binding sites. Therefore calcium will not treat it nor will the highly dangerous bisphosphonate drugs that significantly increase the risk of bone fractures by inhibiting bone remodeling and decreasing bone flexibility.

I was working on a book on osteoporosis, osteomalacia and osteoarthritis and had a while chapter dedicated to explaining why these very dangerous drugs cause these side effects and continue to do so long after the drugs are discontinued.

To treat osteoporosis the bone collagen must be restored. The most important nutrient for doing this is silica, which is absorbed and utilized as orthosilicic acid. Silica also aids in calcium absorption and is responsible for putting minerals in to the bone itself. Next on the list is vitamin C (natural sources are best) since it is also required for collagen formation and a source of the amino acids required such as gelatin.  As the collagen in restored the bones must be stressed such as weight bearing exercise to actually get the minerals in to to the collagen matrix. This is why people who do weight bearing exercises develop higher bone densities and astronauts in space lose bone density since it is hard to put stress on bones in zero gravity.
8
Nutrition Talk / Re: Keto Diet
« Last post by James on September 09, 2018, 01:46:26 AM »
The body actually becomes more adept to burning fat as a fuel source with intense training. Your body only has a very small muscle glycogen store that gets rapidly used up with intense exercise. Then the body is forced to rely on secondary fuel sources as fuel sources for the muscles such as lactate and fatty acids.

I used to race (running and triathlons) and did long distance bicycle touring. Personally I did best on a super high carbohydrate diet back in those days. Higher protein would drop my energy levels drastically after a few days.

It was an old racers trick though to consume an oil before a race to boost endurance. Had to start out slow with like a spoonful of olive oil then gradually working up to a cup of oil before the race to allow the body become accustomed to the large amount of oil. The oil provided more energy than other fuel sources.

I personally though am not a fan of the keto diet. I find it to be very over-hyped and people are ignoring the research showing ketones promote cancer growth. Like these.

Ketones and lactate “fuel” tumor growth and metastasis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047616/

"Ketones are a “super-fuel” for mitochondria, producing more energy than lactate and simultaneously decreasing oxygen consumption.15–17"

"So, just as ketones are a “super-fuel” under conditions of ischemia in the heart and in the brain, they could fulfill a similar function during tumorigenesis, as the hypoxic tumor exceeds its blood supply. Stromal ketone production could obviate the need for tumor angiogenesis. Once ketones are produced and released from stromal cells, they could then be re-utilized by epithelial cancer cells, where they could directly enter the TCA cycle, just like lactate. In this sense, ketones are a more powerful mitochondrial fuel, as compared with lactate."

"Similarly, acute fasting in rodent animal models is also sufficient to dramatically increase tumor growth.22 Both of these experimental conditions (diabetes and fasting/starvation) are known to be highly ketogenic and, thus, are consistent with our current hypothesis that ketone production fuels tumor growth. Finally, given our current findings that ketones increase tumor growth, cancer patients and their dieticians may want to re-consider the use of a “ketogenic diet” as a form of anti-cancer therapy."

Ketone body utilization drives tumor growth and metastasis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507492/

"Thus, the tumor stroma may serve as a reservoir for ketone body production, while cancer cells upregulate the enzymes required for ketone body re-utilization, driving oxidative mitochondrial metabolism (OXPHOS) in epithelial cancer cells (Fig. 9).

To prevent this form of “two-compartment tumor metabolism,” ketone inhibitors should be designed to halt ketone body production in cancer-associated fibroblasts and ketone body re-utilization in epithelial cancer cells. This simple strategy could effectively starve cancer cells to death by “cutting off their fuel supply.”

Finally, it is worth noting that ketogenic fibroblasts were more prone to a loss of stromal Cav-1 expression. In breast cancer patients, a loss of stromal Cav-1 expression is associated with increased tumor recurrence, metastasis, drug resistance and overall poor clinical outcome.10-13 Thus, stromal Cav-1 could be used as a biomarker to select patients that would be more likely to benefit from therapy with ketone inhibitors, allowing biomarker-based treatment stratification and personalized cancer therapy."


Ketone bodies and two-compartment tumor metabolism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507491/

"We have previously suggested that ketone body metabolism is critical for tumor progression and metastasis. Here, using a co-culture system employing human breast cancer cells (MCF7) and hTERT-immortalized fibroblasts, we provide new evidence to directly support this hypothesis. More specifically, we show that the enzymes required for ketone body production are highly upregulated within cancer-associated fibroblasts. This appears to be mechanistically controlled by the stromal expression of caveolin-1 (Cav-1) and/or serum starvation. In addition, treatment with ketone bodies (such as 3-hydroxy-butyrate, and/or butanediol) is sufficient to drive mitochondrial biogenesis in human breast cancer cells. This observation was also validated by unbiased proteomic analysis. Interestingly, an MCT1 inhibitor was sufficient to block the onset of mitochondrial biogenesis in human breast cancer cells, suggesting a possible avenue for anticancer therapy. Finally, using human breast cancer tumor samples, we directly confirmed that the enzymes associated with ketone body production (HMGCS2, HMGCL and BDH1) were preferentially expressed in the tumor stroma. Conversely, enzymes associated with ketone re-utilization (ACAT1) and mitochondrial biogenesis (HSP60) were selectively associated with the epithelial tumor cell compartment. Our current findings are consistent with the "two-compartment tumor metabolism" model. Furthermore, they suggest that we should target ketone body metabolism as a new area for drug discovery, for the prevention and treatment of human cancers."
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Nutrition Talk / Re: Spirulina side effects?
« Last post by James on September 09, 2018, 01:33:41 AM »
Spirulina, which is actually a cyanobacteria and not an algae as is often stated does not detoxify. It is protein rich. Personally I prefer chlorella, which is an algae and detoxfies.

Your increased breakouts can be several things including changes in hormones or even contaminated makeup.
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Nutrition Talk / Re: Women's Health/Osteoporosis/Hormone Replacement
« Last post by susan on September 06, 2018, 06:05:57 PM »
Hi Jennifer,

Your questions and intuition about these challenges and contradictions are very insightful. You are right that there is a lot to be said about these topics! The medications cause digestive distress and lose their effectiveness over time as well. Hormone replacement was thought to be helpful but there are side effects that outweigh any benefit. You are also correct that bone loss measurements are not always reliable and are measured against a healthy 20 something and not compared to the person's bone loss history. You are going to love the Therapeutics semester. Chapters 201 and 202 go into this in great detail. For now it is helpful to support bones and hormone balance with a whole foods diet, avoiding acid forming foods like soda, sugar, caffeine, alcohol, refined white flour and excess animal food consumption.  The younger a person, especially women become mindful and practice this the srtonger their future bones will be later in life. A mineral rich diet will support bone health, a plant dense diet will provide micronutrients that support endocrine function.  Question everything just like you are doing! You will find many contradictions and opinions but if you keep in mind that our role as NC's is to help people build a strong foundation through diet and lifestyle even if you don't know everything you want to know now, you can still help people The cool thing about this profession is that we never stop learning!
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